Properties of Iron-Sulfur Clusters of Complex I/NDH-1

Center Cluster Subunit
Complex I
Bacterial NDH-1
FeS Binding motifs
Em (mV) pH dep Em (mV) pH dep
N1a [2Fe-2S] FP24K/Nqo2/NuoE -370 + (-150?) + CxxxxCx35CxxxC
N1b [2Fe-2S] IP75K/Nqo3/NuoG -250 - -260 - Cx10CxxCx13C
N2 [4Fe-4S] PSST/Nqo6/NuoB(?) -50~-150 + -130 + CCx63Cx29CP
N3 [4Fe-4S] FP51K/Nqo1/NuoF -250 - -240 - CxxCxxCx39C
N4 [4Fe-4S] IP75K/Nqo3/NuoG -250 - -270 - CxxCxxCx42-43C
N5 [4Fe-4S] IP75K/Nqo3/NuoG -250 -   ? HxxxCxxCxxxxxC
N6 2[4Fe-4S] TYKY/Nqo9/NuoI    ?   ? (CxxCxxCxxxCP)2
N7 [4Fe-4S] IP75K/Nqo3/NuoG   ?   ? CxxCxxxCx27C